Examination of immunogenic properties of recombinant antigens based on p22 protein from African swine fever virus

Autor:	Díaz Carlos, Salát Jiří, Břínek Kolařová Dagmar, Celer Vladimír, Frébort Ivo
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	african swine fever virus heat-labile enterotoxin b subunit immune response p22 protein Veterinary medicine SF600-1100
Zdroj:	Journal of Veterinary Research, Vol 66, Iss 3, Pp 297-304 (2022)
Druh dokumentu:	article
ISSN:	2450-8608 14809141
DOI:	10.2478/jvetres-2022-0043
Popis:	The single member of the Asfarviridae family is African swine fever virus (ASFV). This double-stranded DNA virus infects wild and farmed swine and loses the pig industry large sums of money. An inner envelope, capsid, and outer envelope are parts of the ASFV particle containing structural proteins playing different roles in the process of infection or host immune defence evasion. When expressed by the baculovirus system, the p22 protein from the inner envelope was found to induce partial protection against a virulent virus strain. This study aimed to express a part of this protein in a different system and evaluate its immunogenicity.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/5a101f14809141e5b6d9a065af48ef98 Zobrazit plný text záznamu View record in DOAJ