Diagnosis and treatment of IgG4-related ophthalmic disease
| Autor: | Alberto Giuseppe Distefano, Murray Meltzer, Janet Roen, Alan Friedman, Ebby Elahi, Albert Y Wu |
|---|---|
| Jazyk: | English<br />Spanish; Castilian<br />French<br />Portuguese |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Vision Pan-America, Vol 14, Iss 2, Pp 40-45 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2219-4665 2219-4673 |
| DOI: | 10.15324/vpa.v14i2.237 |
| Popis: | Purpose: To further characterize the clinical presentation, diagnosis, and current treatment strategies of IgG4-related ophthalmic disease. Methods: Review and analysis of seven cases orbital inflammatory syndrome found to be biopsy positive for IgG4. Results: We present seven cases of IgG4-related ophthalmic disease, a previously unknown entity that has only recently been identified as a treatable systemic disorder. Management included surgical excision, systemic steroids, steroid-sparing immunosuppression, and radiotherapy. Conclusions: These cases illustrate the importance of including IgG4-related ophthalmic disease in the differential diagnosis of periorbital or orbital masses. Prompt recognition of this entity by clinicians can allow for effective treatment with corticosteroids. Treatment with steroid-sparing immune suppressants and radiotherapy has shown promise in chronic or refractory disease, nonetheless tumor excision may ultimately be necessary. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|