Adjuvant immunotherapy and targeted therapy in early and locally advanced resectable lung cancer: expanding treatment tentacles?

Autor: Evaggelos Fergadis, Amadea Heitmann, Theodore Tsaras, Georgia Hardavella
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Breathe, Vol 20, Iss 2 (2024)
Druh dokumentu: article
ISSN: 1810-6838
2073-4735
20734735
DOI: 10.1183/20734735.0035-2024
Popis: Adjuvant platinum-based chemotherapy has been the main treatment following surgical resection with curative intent in early and locally advanced nonsmall cell lung cancer (NSCLC) albeit with a 5% improvement in 5-year survival rates. Recent advances in biomarkers pave the way for targeted treatments and immunotherapy in a broader spectrum of patients with subsequently improved clinical outcomes. Targeted treatments and immunotherapy have established their place in the adjuvant setting of resected NSCLC.
Databáze: Directory of Open Access Journals