Carrot Juice Consumption Reduces High Fructose-Induced Adiposity in Rats and Body Weight and BMI in Type 2 Diabetic Subjects
Autor: | Malleswarapu Mahesh, Himanshi Pandey, Mooli Raja Gopal Reddy, Prashanti Prabhakaran Sobhana, Damayanti Korrapati, Putcha Uday Kumar, Ayyalasomayajula Vajreswari, Shanmugam Murugaiha Jeyakumar |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | Nutrition and Metabolic Insights, Vol 14 (2021) |
Druh dokumentu: | article |
ISSN: | 1178-6388 11786388 |
DOI: | 10.1177/11786388211014917 |
Popis: | Nutritional intervention is a key strategy in the control and management of non-communicable diseases. Here, initially, we evaluated the effects of carrot juice (CJ) on some of the physical and biochemical parameters in rats fed with high-fructose diet, then in type 2 diabetic subjects. For the animal study, weanling male Wistar rats were given control (n = 6) or high fructose (HFr; n = 24) diet for 8 weeks. Then, the HFr group rats were subdivided into 4 groups (n = 6 in each) and continued either on HFr diet or shifted to control diet, with or without CJ (0.3 mg β-carotene) ingestion orally for 8 weeks. At the end, the ingestion of CJ reversed the HFr-induced adiposity (23 ± 1.6 vs 18 ± 1.1, P = .038), hypertriglyceridemia (182 ± 18.2 vs 90 ± 10.5 mg/dL, P |
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