Pharmacological vs Exercise Stress Echocardiography for Detection of Cardiac Allograft Vasculopathy

Autor: Milena A. Gebska, MD, PhD, Noah N. Williford, MD, Angela J. Schadler, DNP, MHCDS, ARNP, Carolyn Laxson, MA, RN, CCTC, Paulino Alvarez, MD, Alexandros Briasoulis, MD, PhD, Linda M. Cadaret, MD, Ily Kristine T. Yumul-Non, MD, Richard E. Kerber, MD, Robert M. Weiss, MD
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 4, Iss 1, Pp 65-75 (2020)
Druh dokumentu: article
ISSN: 2542-4548
DOI: 10.1016/j.mayocpiqo.2019.09.003
Popis: Objective: To test the hypothesis that exercise and dobutamine would provide levels of cardiac stress that are comparable to those achieved in a general stress test population, and to one another, in heart transplant recipients. Patients and Methods: From February 10, 2015, to December 31, 2017, 81 patients underwent exercise stress (N=45) or dobutamine stress (N=36) echocardiography at a mean ± SD of 11±14 years (range, 1-29 years) after heart transplant. Hemodynamic and inotropic responses were compared between groups, and to a prior test, longitudinally. The primary outcome was peak heart rate (HR) × systolic blood pressure (SBP). Results: Peak exercise HR × SBP × 10−3 was a mean ± SD of 24.9±4.9 mm Hg/min for exercise stress vs 21.2±3.4 mm Hg/min during dobutamine stress (P
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