Meta‐Analysis Global Group in Chronic Heart Failure score for the prediction of mortality in valvular heart disease

Autor: Junxing Lv, Haiyan Xu, Yunqing Ye, Zhe Li, Weiwei Wang, Bin Zhang, Qinghao Zhao, Haitong Zhang, Zhenyan Zhao, Qingrong Liu, Bincheng Wang, Zhenya Duan, Zikai Yu, Shuai Guo, Yanyan Zhao, Runlin Gao, Junbo Ge, Yongjian Wu, CHINA‐VHD collaborators
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: ESC Heart Failure, Vol 11, Iss 1, Pp 349-365 (2024)
Druh dokumentu: article
ISSN: 2055-5822
DOI: 10.1002/ehf2.14586
Popis: Abstract Aims Valvular heart disease (VHD) is one of the leading causes of heart failure. Clinically significant VHD can induce different patterns of cardiac remodelling, and risk stratification is challenging in patients with various degrees of cardiac dysfunction. The study aimed to investigate the prognostic implications of Meta‐Analysis Global Group in Chronic Heart Failure (MAGGIC) score in patients with VHD. Methods and results This study used data from the China Valvular Heart Disease (China‐VHD) registry, which was a multicentre, prospective, observational cohort study for patients with significant (at least moderate) VHD. In total, 10 446 patients with moderate or greater VHD from the China‐VHD study were included in the present analysis. The primary outcome of interest was all‐cause mortality within 2 years. Among 10 446 patients with VHD, the mean age was 61.98 ± 13.47 years, and 5819 (55.7%) were male. During 2 years of follow‐up, 895 (8.6%) patients died. The MAGGIC score was monotonically and independently associated with mortality in both total cohort [adjusted hazard ratio: 1.095, 95% confidence interval (CI): 1.084–1.107, P
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