| Autor: |
Jennifer L. Cadnum, Daniel Li, Sarah N. Redmond, Amrita R. John, Basya Pearlmutter, Curtis Donskey |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Pathogens and Immunity, Vol 5, Iss 1, Pp 52-67 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2469-2964 |
| DOI: |
10.20411/pai.v5i1.372 |
| Popis: |
Background-Shortages of personal protective equipment (PPE) including N95 filtering facepiece respirators is an urgent concern in the setting of the global COVID-19 pandemic. Decontamination of PPE could be useful to maintain adequate supplies, but there is uncertainty regarding the efficacy of decontamination technologies. Methods-A modification of the American Society for Testing and Materials standard quantitative carrier disk test method (ASTM E-2197-11) was used to examine the effectiveness of ultraviolet-C (UV-C) light, a high-level disinfection cabinet that generates aerosolized peracetic acid and hydrogen peroxide, and dry heat at 70°C for 30 minutes for decontamination of bacteriophages Phi6 and MS2 and methicillin-resistant Staphylococcus aureus (MRSA) inoculated onto 3 commercial N95 respirators. Three and 6 log10 reductions on N95 respirators were considered effective for decontamination and disinfection, respectively. Results-UV-C administered as a 1-minute cycle in a UV-C box or a 30-minute cycle by a room decontamination device reduced contamination but did not meet criteria for decontamination of the viruses from all sites for any of the N95s. The high-level disinfection cabinet was effective for decontamination of all the organisms from the N95s and achieved disinfection with 3 disinfection cycles over ~60 minutes. Dry heat at 70°C for 30 minutes was not effective for decontamination of the bacteriophages. Conclusions-UV-C could be useful to reduce contamination on N95 respirators. However, the UV-C technologies studied did not meet our criteria for decontamination under the test conditions used. The high-level disinfection cabinet was effective for decontamination of N95s and met criteria for disinfection with multiple cycles. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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