N‐terminal pro‐B‐type natriuretic peptide concentrations, testing and associations with worsening heart failure events

Autor: Giulia Ferrannini, Lina Benson, Dominik Lautsch, Ulf Dahlström, Lars H. Lund, Gianluigi Savarese, Juan Jesus Carrero
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: ESC Heart Failure, Vol 11, Iss 2, Pp 759-771 (2024)
Druh dokumentu: article
ISSN: 2055-5822
DOI: 10.1002/ehf2.14613
Popis: Abstract Aims In patients with heart failure (HF), we aimed to assess (i) the time trends in N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) testing; (ii) patient characteristics associated with NT‐proBNP testing; (iii) distribution of NT‐proBNP levels, focusing on the subgroups with (WHFE) vs. without (NWHFE) a worsening HF event, defined as an HF hospitalization; and (iv) changes of NT‐proBNP levels over time. Methods and results NT‐proBNP testing and levels were investigated in HF patients enrolled in the Swedish Heart Failure Registry (SwedeHF) linked with the Stockholm CREAtinine Measurements project from January 2011 to December 2018. Index date was the first registration in SwedeHF. Patterns of change in NT‐proBNP levels before (in the previous 6 ± 3 months) and after (in the following 6 ± 3 months) the index date were categorized as follows: (i)
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