| Autor: |
Patricia Rezende do Prado, Rosalina Jorge Koifman, Ilce Ferreira da Silva |
| Jazyk: |
English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: |
2014 |
| Předmět: |
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| Zdroj: |
Cadernos de Saúde Pública, Vol 30, Iss 9, Pp 1912-1920 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
0102-311X |
| DOI: |
10.1590/0102-311X00164913 |
| Popis: |
The objective of the study was to determine the dynamics of precancerous lesions in women of a cohort treated for cervical intraepithelial neoplasia (CIN) and followed up over the next two years. The conditional probability of failure was calculated using the Kaplan-Meier method, and the raw and adjusted hazard ratios (HR) were determined using Cox regression with a p-value entry of < 0.05. Of the 237 women who were treated, 51.5% were accompanied over 24 months, and treatment failed for 21.9% of those accompanied. Women who had five or more pregnancies (adjusted HR = 3.10, 95%CI: 1.28-7.51) or an initial histological diagnosis of CIN II/III demonstrated an independent risk of treatment failure (adjusted HR = 3.14, 95%CI: 1.20-8.19). Being in a stable relationship was a protective factor against treatment failure (adjusted HR = 0.47, 95%CI: 0.24-0.89). A history of more frequent pregnancies and a histological diagnosis of CIN II/III are directly correlated with risk of CIN treatment failure, whereas being in a stable relationship is inversely correlated with this risk. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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