SYNTHESIS, X-RAY AND ANTIMICROBIAL ACTIVITY OF ISATIN-3-PHENYLHYDRAZONE

Autor: SANDRA S. KONSTANTINOVIĆ, AGNEŠ KAPOR, BLAGA C. RADOVANOVIĆ, ANDREA DEAK
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Chemical Industry and Chemical Engineering Quarterly, Vol 14, Iss 1, Pp 27-34 (2008)
Druh dokumentu: article
ISSN: 1451-9372
Popis: Isatin-3-phenylhydrazone was synthesized and X-ray crystal structure of this compound has been solved. Its structure was also established using FTIR, UV/Vis and 1H-NMR spectroscopic method. The compound was tested for antimicrobial activity against Staphylococcus aureus, Bacillus subtilus, Enterococcus D, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and Candida albicans. Stability of isatin-3-phenylhydrazone toward UV-A irradiation has been studied in this work. Isatin derivative undergoes bleaching following first-order kinetics.
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