Serum Vitamin D and Parathyroid Hormone Levels in Patients with Obstructive Sleep Apnea Syndrome

Autor: Fırat Uygur, Ali Erdem Baki, Hakan Tanrıverdi, Tacettin Örnek, Figen Atalay
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: İstanbul Medical Journal, Vol 17, Iss 2, Pp 64-67 (2016)
Druh dokumentu: article
ISSN: 2619-9793
2148-094X
DOI: 10.5152/imj.2016.55265
Popis: Introduction: An increase in sympathetic activity caused by intermittent hypoxia and reoxygenation that develops an obstruction of the upper respiratory tract in obstructive sleep apnea syndrome (OSAS) results in cardiovascular and metabolic changes. This study aimed to assess the effects of OSAS on serum vitamin D and parathyroid hormone (PTH) levels.Methods: The study population comprised 103 male patients with newly diagnosed OSAS and 58 male non-apnoeic controls matched for age, sex, and body mass index (BMI). Serum calcium, phosphorus, vitamin D, and PTH levels were measured.Results: There were no significant differences between patients with OSAS and the controls in terms of age, sex, BMI, smoking status, hypertension, and hyperlipidemia. Serum vitamin D levels were significantly lower in the OSAS group than in the control group (22.4±7.5 ng/mL vs. 31±7.9 ng/mL, respectively; p
Databáze: Directory of Open Access Journals