Evaluation of Short-term Memory, Working Memory, and Executive Functions in Patients with Relapsing-remitting Multiple Sclerosis

Autor: Furkan Duman, Handan Can, Alev Leventoğlu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Türk Nöroloji Dergisi, Vol 28, Iss 3, Pp 162-168 (2022)
Druh dokumentu: article
ISSN: 1309-2545
DOI: 10.4274/tnd.2022.24992
Popis: Objective: To compare patients with relapsing-remitting multiple sclerosis (RRMS) and healthy individuals in terms of short-term memory (STM), working memory (WM) and executive functions. Materials and Methods: The sample consisted of 33 patients with RRMS and 26 healthy participants. The groups were matched in terms of age, gender, level of education and hand dominance. The socio-demographic characteristics of the participants were recorded; and they were evaluated with Beck depression inventory and state/trait anxiety inventory. Visual aural digit span test B form, Wisconsin card sorting test, backward digit span task, stroop test T-BAG form, Wechsler memory scale: Revised form visual memory span subtest (WMS-R/VMS) and trail making test (TMT) for cognitive functions. Results: There was no statistically significant difference between groups in terms of depression and anxiety scores (p>0.05). Backward visual memory span calculated from WMS-R/VMS was significantly lower (p0.05). Conclusion: Results of this study indicate that patients with RRMS have lower visuo-spatial sketchpad capacity in their WM. However, there was no significant difference between patients with RRMS and healthy controls in terms of verbal and visuo-spatial STM capacity, phonological loop capacity in WM, perseveration, conceptualization, inhibition and set shifting skills.
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