Role of the hormonal system 'Vitamin D/Vitamin D receptors' in the formation of some pregnancy complications
| Autor: | G. S. Manasova, A. G. Andrievsky, N. V. Didenkul, I. V. Shpak, M. I. Turchyn, N. V. Kuzmin |
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| Jazyk: | English<br />Russian<br />Ukrainian |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Репродуктивная эндокринология, Vol 0, Iss 51, Pp 65-68 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2309-4117 2411-1295 |
| DOI: | 10.18370/2309-4117.2020.51.65-68 |
| Popis: | Introduction. The hormonal system “vitamin D/vitamin D receptors” (VD/VDR) is involved in the regulation of numerous physiological processes. VD lack or deficiency is associated with a number of different diseases, including pregnancy complications. Purpose of the study: to determine VD status and its effect on the course of the gestational process in women from the southern region of Ukraine. Materials and methods. 459 women were examined, 318 (69.3%) of them were the main group and 141 (30.7%) were the comparison group. In addition to standard general clinical examinations, ELISA on a COBAS Integra 400 Plus analyzer (Roche Diagnostics, Switzerland) the VD level was determined in the blood. Results and discussion. 49.9% of the pregnant women in the main group had insufficient VD level (25.45 ± 4.63 ng/ml), in 19.4% it corresponded to a deficit (15.28 ± 4.78 ng/ml). VD concentration in the comparison group was 43.38 ± 9.67 ng/ml (p |
| Databáze: | Directory of Open Access Journals |
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