Autor: |
Author Nan Lang, Yuan Zhong, Wenkun Lei, Yiwen Xiao, Yaming Hang, Ya Xie, Zhangwei Lv, Yumin Zhang, Xinyao Liu, Minlu Liang, Congjie Zhang, Pei Zhang, Hua Yang, Yun Wu, Qiuyu Wang, Kun Yang, Jing Long, Yuan Liu, Suhong Wang, Yibin Tang, Maochun Lei, Danyu Zhang, Lichen Ouyang, Liping Zhang, Chun Wang |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Comprehensive Psychiatry, Vol 133, Iss , Pp 152487- (2024) |
Druh dokumentu: |
article |
ISSN: |
0010-440X |
DOI: |
10.1016/j.comppsych.2024.152487 |
Popis: |
Background: The incidence of non-suicidal self-injury (NSSI) has been on the rise in recent years. Studies have shown that people with NSSI have difficulties in emotion regulation and cognitive control. In addition, some studies have investigated the cognitive emotion regulation of people with NSSI which found that they have difficulties in cognitive emotion regulation, but there was a lack of research on cognitive emotion regulation strategies and related neural mechanisms. Methods: This study included 117 people with NSSI (age = 19.47 ± 5.13, male = 17) and 84 non-NSSI participants (age = 19.86 ± 4.14, male = 16). People with NSSI met the DSM-5 diagnostic criteria, and non-NSSI participants had no mental or physical disorders. The study collected all participants' data of Cognitive Emotion Regulation Questionnaire (CERQ) and functional magnetic resonance imaging (fMRI) to explore the differences in psychological performance and brain between two groups. Afterwards, Machine learning was used to select the found differential brain regions to obtain the highest correlation regions with NSSI. Then, Allen's Human Brain Atlas database was used to compare with the information on the abnormal brain regions of people with NSSI to find the genetic information related to NSSI. In addition, gene enrichment analysis was carried out to find the related pathways and specific cells that may have differences. Results: The differences between NSSI participants and non-NSSI participants were as follows: positive refocusing (t = −4.74, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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