Features of Microbiota in Newborns in Critical Condition at Admission to the Intensive Care Unit of a Specialized Hospital

Autor: Yu. S. Aleksandrovich, D. O. Ivanov, E. Yu. Pavlovskaya, K. V. Pshenisnov, A. M. Savicheva, K. V. Shalepo, T. I. Akimenko, D. A. Zemlyanoy
Jazyk: ruština
Rok vydání: 2022
Předmět:
Zdroj: Вестник анестезиологии и реаниматологии, Vol 19, Iss 2, Pp 56-63 (2022)
Druh dokumentu: article
ISSN: 2078-5658
2541-8653
DOI: 10.21292/2078-5658-2022-19-2-56-63
Popis: Clarification of etiology and identification of infectious agents in critically ill newborns is a very urgent problem of neonatal resuscitation.The objective. To study the characteristics of microbiota in critically ill newborns at admission to the intensive care unit (ICU) of a specialized hospital.Subjects and Methods. 165 critically ill newborns were examined, and bacteriological tests of blood, feces, and saliva were performed.Results. Positive culture results were obtained in 40 (24%) patients. The most frequent causative agent was S. epidermidis (47.5%). The detection rate of E. faecalis amounted to 15%, S. haemolyticus ‒ 15%, C. albicans – 12.5%, and K. pneumoniae ‒ 10%. Microorganisms were isolated from feces in 70% of cases, from the oral cavity in 62.5%, and from blood in 12.5%. E. faecalis was equally frequent at all three sites (5%).Conclusion. In 76% of patients, no neonatal infectious agent was isolated at admission to ICU of a specialized hospital that is most likely associated with the early administration of antibacterial drugs in the first hours of life of the newborn.
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