Radiation injuries of organs and tissues: mechanisms of occurrence, methods of prevention and treatment: A review
| Autor: | Daiana A. Balaeva, Denis S. Romanov, Oxana P. Trofimova, Zarina Z. Gadzhibabaeva, Yury Yu. Gorchak, Garia A. Gariaev |
|---|---|
| Jazyk: | ruština |
| Rok vydání: | 2023 |
| Předmět: |
radiation therapy
side effects of radiation therapy radiation proctitis radiation myelitis radiation cystitis radiation alopecia pneumofibrosis radiation pneumonitis radiation esophagitis radiation hepatitis radiation dermatitis Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
| Zdroj: | Современная онкология, Vol 25, Iss 4, Pp 504-512 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1815-1434 1815-1442 18151434 |
| DOI: | 10.26442/18151434.2023.4.202572 |
| Popis: | In modern medicine, radiation therapy (RT) is one of the main therapies for cancer. According to the World Health Organization, about 70% of patients diagnosed with cancer require RT at some stage of treatment. Development and improvement of methods for early diagnosis of cancers, multimodal therapy for cancer patients, including surgical intervention, new drug treatment regimens, modern methods of conformal 3D-RT and proton therapy significantly improved the treatment outcomes of patients and increased their life expectancy. Modern RT is a high-tech chain of sequential use of complex technical devices and mathematical calculations to destroy the tumor without adversely affecting the surrounding normal tissues. Some patients develop radiation injuries to normal organs and tissues that reduce their quality of life. Prevention and treatment of such injuries are urgent problems of modern oncology. The article addresses the pathogenesis and mechanism of the development of systemic and local radiation responses, as well as methods of treatment and prevention of some of them. Three electronic databases, including PubMed, Cochrane and EMBASE, and Russian radiotherapists' publications, were used for systematic review in the information retrieval process. |
| Databáze: | Directory of Open Access Journals |
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