Physiology-Based Revascularization

Autor: Joo Myung Lee, MD, MPH, PhD, Seung Hun Lee, MD, PhD, Doosup Shin, MD, Ki Hong Choi, MD, Tim P. van de Hoef, MD, PhD, Hyun Kuk Kim, MD, PhD, Habib Samady, MD, PhD, Tsunekazu Kakuta, MD, PhD, Hitoshi Matsuo, MD, PhD, Bon-Kwon Koo, MD, PhD, William F. Fearon, MD, Javier Escaned, MD, PhD
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: JACC: Asia, Vol 1, Iss 1, Pp 14-36 (2021)
Druh dokumentu: article
ISSN: 2772-3747
DOI: 10.1016/j.jacasi.2021.03.002
Popis: Coronary physiological assessment using fractional flow reserve or nonhyperemic pressure ratios has become a standard of care for patients with coronary atherosclerotic disease. However, most evidence has focused on the pre-interventional use of physiological assessment to aid revascularization decision-making, whereas post-interventional physiological assessment has not been well established. Although evidence for supporting the role of post-interventional physiological assessment to optimize immediate revascularization results and long-term prognosis has been reported, a more thorough understanding of these data is crucial in incorporating post-interventional physiological assessment into daily practice. Recent scientific efforts have also focused on the potential role of pre-interventional fractional flow reserve or nonhyperemic pressure ratio pullback tracings to characterize patterns of coronary atherosclerotic disease to better predict post-interventional physiological outcomes, and thereby identify the appropriate revascularization target. Pre-interventional pullback tracings with dedicated post-processing methods can provide characterization of focal versus diffuse disease or major gradient versus minor gradient stenosis, which would result in different post-interventional physiological results. This review provides a comprehensive look at the current evidence regarding the evolving role of physiological assessment as a functional optimization tool for the entire process of revascularization, and not merely as a pre-interventional tool for revascularization decision-making.
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