Identification of the Bisphenol A (BPA) and the Two Analogues BPS and BPF in Cryptorchidism

Autor: Marta Diana Komarowska, Kamil Grubczak, Jan Czerniecki, Adam Hermanowicz, Justyna Magdalena Hermanowicz, Wojciech Debek, Ewa Matuszczak
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Endocrinology, Vol 12 (2021)
Druh dokumentu: article
ISSN: 1664-2392
DOI: 10.3389/fendo.2021.694669
Popis: Objectiveto explore the association of plasma concentrations of bisphenol A (BPA), bisphenol S (BPS), and bisphenol F (BPF) with unilateral cryptorchidism. In addition, to analyze selected demographic and intraoperative characteristics.DesignRetrospective analysis to determine plasma concentrations of total BPA, BPS and BPF using gas chromatography - mass spectrometry (GC-MS) among prepubertal boys with cryptorchidism and prebupertal male control subjects. During operation, the size, turgor and location of the cryptorchid testes were assessed.Main Outcome MeasurePlasma concentrations of total BPA, BPS and BPF.ResultsIn children with cryptorchidism, plasma levels of BPA, BPS and BPF were significantly higher compared to the control subjects. For BPA, it was: median value: 9.95 ng/mL vs. 5.54 ng/mL, p
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