Clinical experience with piribedil in chronic cerebrovascular disease with cognitive impairment

Autor: E. V. Moroz, T. A. Zakharycheva, M. V. Antonyuk
Jazyk: ruština
Rok vydání: 2019
Předmět:
Zdroj: Неврология, нейропсихиатрия, психосоматика, Vol 11, Iss 4, Pp 100-103 (2019)
Druh dokumentu: article
ISSN: 2074-2711
2310-1342
DOI: 10.14412/2074-2711-2019-4-100-103
Popis: Objective: to evaluate the effect of piribedil on cognitive functions in elderly patients with chronic cerebrovascular disease (CCVD) and cognitive impairment (CI). Patients and methods. A total of 67 patients aged 60-75 years with CCVD and CI were examined. A control group included 32 patients who had received basic therapy with antihypertensive and, if indicated, lipid-lowering and antithrombotic drugs. A study group consisted of 35 patients who additionally took piribedil 50 mg after evening meals for 3 months. Neuropsychological examination was made before and after a treatment cycle. Results and discussion. After 3 months, only the piribedil group showed a significant neuropsychological improvement (p
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