| Autor: |
Nele Villabruna, Ray W. Izquierdo-Lara, Claudia M. E. Schapendonk, Erwin de Bruin, Felicity Chandler, Tran Thi Nhu Thao, Brenda M. Westerhuis, Janko van Beek, Louise Sigfrid, Carlo Giaquinto, Herman Goossens, Julia A. Bielicki, Malte Kohns Vasconcelos, Pieter L. A. Fraaij, Marion P. G. Koopmans, Miranda de Graaf |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-022-18383-6 |
| Popis: |
Abstract Norovirus is a leading cause of epidemic acute gastroenteritis. More than 30 genotypes circulate in humans, some are common, and others are only sporadically detected. Here, we investigated whether serology can be used to determine which genotypes infect children. We established a multiplex protein microarray with structural and non-structural norovirus antigens that allowed simultaneous antibody testing against 30 human GI and GII genotypes. Antibody responses of sera obtained from 287 children aged |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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