Heterologous Covid-19 vaccines intervention effect on reactogenicity

Autor: Wajeha Najeeb, Palvasha Waheed, Rehana Khadim
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of the Pakistan Medical Association, Vol 74, Iss 1 (2023)
Druh dokumentu: article
ISSN: 0030-9982
DOI: 10.47391/JPMA.8615
Popis: To determine the change in the occurrence of short-term vaccine reactions on the use of heterologous Covid-19 booster, a single centre short-term study of two months duration was conducted. It was designed as an interventional study with registered clinical trial number # SLCTR/2022/008. It was conducted on medical students and faculty of a National university of medical sciences, Rawalpindi affiliated public sector medical college. A total of 348 individuals were administered with Ad5-nCoV vaccine and 101 with mRNA-1273 vaccine. They all had been previously vaccinated with two doses of BBIBP-CorV. BBIBP-CorV reactogenicity was considered a control group. Vaccine reactions, including pain and redness at the injection site, fever, no observed reactions at all, myalgia, feeling cold, dizziness, paraesthesia in the arm, light-headedness, had a significant change in their frequencies in comparison to homologous vaccine (BBIBP-CorV) reactogenicity. ---Continue
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