BNP and NT-proBNP as Diagnostic Biomarkers for Cardiac Dysfunction in Both Clinical and Forensic Medicine

Autor:	Zhipeng Cao, Yuqing Jia, Baoli Zhu
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	BNP NT-proBNP heart failure cardiac dysfunction forensic medicine postmortem biochemistry Biology (General) QH301-705.5 Chemistry QD1-999
Zdroj:	International Journal of Molecular Sciences, Vol 20, Iss 8, p 1820 (2019)
Druh dokumentu:	article
ISSN:	1422-0067 20081820
DOI:	10.3390/ijms20081820
Popis:	Currently, brain natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) are widely used as diagnostic biomarkers for heart failure (HF) and cardiac dysfunction in clinical medicine. They are also used as postmortem biomarkers reflecting cardiac function of the deceased before death in forensic medicine. Several previous studies have reviewed BNP and NT-proBNP in clinical medicine, however, few articles have reviewed their application in forensic medicine. The present article reviews the biological features, the research and application status, and the future research prospects of BNP and NT-proBNP in both clinical medicine and forensic medicine, thereby providing valuable assistance for clinicians and forensic pathologists.
Databáze:	Directory of Open Access Journals
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