Autor: |
Shuang-Chun Liu, Lei Xia, Jin Zhang, Xue-Hong Lu, Da-Kang Hu, Hai-Tao Zhang, Hai-Jun Li |
Jazyk: |
angličtina |
Rok vydání: |
2015 |
Předmět: |
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Zdroj: |
PLoS ONE, Vol 10, Iss 7, p e0134088 (2015) |
Druh dokumentu: |
article |
ISSN: |
1932-6203 |
DOI: |
10.1371/journal.pone.0134088 |
Popis: |
IntroductionA high incidence of myocardial infarction among patients with gout has been suggested by several observational studies. We performed a meta-analysis to evaluate the association between gout and the risk of myocardial infarction.Materials and methodsThe PubMed and Embase databases were searched from inception to October 2014 for cohort studies that evaluating the association between gout and the risk of myocardial infarction. Summary estimates were derived using a random-effects model and reported as relative risks (RRs) with 95% confidence intervals (CIs).ResultsFive studies involving 8,656,413 participants with a total of 1000 MI events were included. Overall, gout was associated with an increased risk of myocardial infarction (RR 1.45; 95% CI, 1.19-1.75; pConclusionThis meta-analysis suggests that patients with gout have an increased risk of myocardial infarction. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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