The Role of Surveillance Inspections in Reducing False-Positives of SARS-CoV-2 Omicron Variants during the COVID-19 Epidemic

Autor: Li-Li Liu, Yu-Hong Zheng, You-Quan Zhang, Jin-Piao Lin, Zhi-Lin Luo, Liu-Min Yu, Shi-Hua Gao, Falin Chen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Canadian Journal of Infectious Diseases and Medical Microbiology, Vol 2023 (2023)
Druh dokumentu: article
ISSN: 1918-1493
DOI: 10.1155/2023/8508975
Popis: Objective. This study aims to assess the effectiveness of surveillance inspections conducted by the provincial health committee in Quanzhou city during a COVID-19 outbreak in reducing false-positive results in SARS-CoV-2 RT-PCR assays. Method. The team conducted on-site inspections of laboratories that participated in mass screening, recording any violations of rules. Results. The positive cases in five rounds of mass screening were 23, 173, and 4 in Licheng District, Fengze District, and Luojang District, respectively. The false-positive rates in the five rounds of mass screening were 0.0099%, 0.0063%, 0.0018%, 0.0006%, and 0%, respectively. The study also recorded that the number of violations in the seven selected laboratories was 36, 68, 69, 42, 60, 54 and 47. The corresponding false-positive rates were 0.0012%, 0.0060%, 0.0082%, 0.0032%, 0.0060%, 0.0027%, and 0.0021%, respectively. The study found a positive correlation between false-positive rates and the number of violations (r = 0.905, P=0.005), and an inverse correlation between false-positive rates and the frequency of surveillance inspections (r = −0.950, P
Databáze: Directory of Open Access Journals
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