INFLUÊNCIA DO MÉTODO EXTRATIVO NO TEOR DE FLAVONOIDES DE Cnidoscolus quercifolius POHL (EUPHORBIACEAE) E ATIVIDADE ANTIOXIDANTE
Autor: | Daniel da S. Torres, Emanuella C. V. Pereira, Pedrita A. Sampaio, Nathália A. C. de Souza, Christiane A. A. Ferraz, Ana P. de Oliveira, Celuane A. Moura, Jackson R. G. S. Almeida, Pedro J. Rolim-Neto, Raimundo G. de Oliveira-Júnior, Larissa A. Rolim |
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Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
Předmět: | |
Zdroj: | Química Nova, Vol 41, Iss 7, Pp 743-747 |
Druh dokumentu: | article |
ISSN: | 1678-7064 0100-4042 |
DOI: | 10.21577/0100-4042.20170236 |
Popis: | Cnidoscolus quercifolius Pohl is a Brazilian medicinal plant from Caatinga biome and possesses several pharmacological properties. Phytochemical investigations have attributed some of these properties to the presence of flavonoids. In this paper, we report the influence of the extraction process on the flavonoid content obtained from leaves of C. quercifolius and its antioxidant activity. A factorial design 22 was performed, using temperature and agitation as independent variables. Qualitative and quantitative analyzes of the extracts were performed by HPLC-DAD. Rutin and apigenin were identified in the extracts and chosen as analytical markers. Pareto chart and Surface response plots suggested that rutin content was increased up to 3.93 times when temperature was employed during the extraction process. However, apigenin content was significantly reduced in the method whose temperature or agitation were used (p |
Databáze: | Directory of Open Access Journals |
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