Oncologic impact of concomitant prostate cancer characteristics at the time of radical cystoprostatectomy for bladder cancer: a population-based analysis

Autor: Mykyta Kachanov, Malte W. Vetterlein, Armin Soave, Pierre I. Karakiewicz, Nikolaos Liakos, Thomas Jankowski, Randi M. Pose, Mikolaj Mendrek, Margit Fisch, Jorn H. Witt, Markus Graefen, Sami-Ramzi Leyh-Bannurah
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: The Aging Male, Vol 25, Iss 1, Pp 47-54 (2022)
Druh dokumentu: article
ISSN: 1368-5538
1473-0790
13685538
DOI: 10.1080/13685538.2022.2040982
Popis: Objective The aim of this study was to evaluate the prognostic impact of concomitant prostate cancer (PCa) of the cancer-specific mortality (CSM) in the aging patient’s papulation with bladder cancer (BCa) treated with radical cystoprostatectomy (RCP). Materials and Methods Within the SEER database (2004–2015), 1468 patients were treated with RCP for BCa harboring histopathological PCa findings. To account for other cause mortality (OCM), multivariable competing risk regression (CRR) tested for potential BCa-CSM differences according to PCa characteristics risk factors predicting CSM Results CRR analysis revealed that only following BCa characteristics, as high pathological tumor stages(Ta/Tis/T1 [REF.] vs. T2; HR 2.03, 95% CI: 1.16-3.57, p = 0.014 vs. T3; HR 4.32, 95% CI: 2.45-7.61, p
Databáze: Directory of Open Access Journals
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