Primary vulval mucinous adenocarcinoma of intestinal type masquerading as Bartholin's cyst

Autor: Kalaivani Selvi Subramanian, Jinkala Sreerekha, Bhawana Ashok Badhe, Prasanth Penumadu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Advanced Medical and Health Research, Vol 9, Iss 1, Pp 49-51 (2022)
Druh dokumentu: article
ISSN: 2349-4220
2350-0298
DOI: 10.4103/ijamr.ijamr_190_21
Popis: Vulval carcinomas are rare and account for 3%–5% of female genital tract malignancies. Primary vulval adenocarcinoma of intestinal type is an extremely rare tumor which is considered metastatic until otherwise proven with very few case reports available in the literature. A 58-year-old woman presented with recurrent swelling in the genital region associated with pain. She had a past history of surgery done for Bartholin's cyst which was reported as adenocarcinoma. She underwent radical vulvectomy for the recurrent tumor which showed features of adenocarcinoma with glandular and papillary pattern with abundant extracellular mucin production and immunohistochemical (IHC) features favoring a diagnosis of primary vulval mucinous adenocarcinoma of intestinal type after excluding metastasis from other sites. As morphology cannot differentiate it from metastasis, a thorough investigation to rule out any primary in the gastrointestinal tract with a minimum IHC panel of markers including cytokeratin (CK) 20, CK7, carcinoembryonic antigen, and caudal-related homeobox 2 can help in confirming the diagnosis.
Databáze: Directory of Open Access Journals