Impact of frailty on outcomes and readmissions after transcatheter and surgical aortic valve replacement in a national cohortCentral MessagePerspective

Autor: Travis J. Miles, MD, Christopher T. Ryan, MD, Katie J. Hogan, PhD, Bhavesh S. Sayal, BS, Christopher B. Sylvester, MD, PhD, Todd K. Rosengart, MD, Joseph S. Coselli, MD, Marc R. Moon, MD, Ravi K. Ghanta, MD, Subhasis Chatterjee, MD
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: JTCVS Open, Vol 20, Iss , Pp 14-25 (2024)
Druh dokumentu: article
ISSN: 2666-2736
DOI: 10.1016/j.xjon.2024.05.006
Popis: Objective: We examined the effect of frailty on in-hospital mortality, readmission rates, and hospitalization costs after transcatheter and surgical aortic valve replacement in a population-level cohort. Methods: The Nationwide Readmissions Database was queried for patients who underwent transcatheter or surgical aortic valve replacement during 2016-2018. Multivariate logistic regression was used to discern independent effects of frailty on outcomes. Kaplan–Meier time-to-event analysis was used to evaluate the effect of frailty on freedom from readmission. Results: A total of 243,619 patients underwent aortic valve replacement: 142,786 (58.6%) transcatheter aortic valve replacements and 100,833 (41.4%) surgical aortic valve replacements. Frail patients constituted 16,388 (11.5%) and 7251 (7.2%) in the transcatheter aortic valve replacement and surgical aortic valve replacement cohorts, respectively. Compared with nonfrail patients, frail patients had greater in-hospital mortality (transcatheter aortic valve replacement: 3.2% vs 1.1%; surgical aortic valve replacement: 6.1% vs 2.0%; both P
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