A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression

Autor: Chrysanthi Taxiarchi, Andrea Beaghton, Nayomi Illansinhage Don, Kyros Kyrou, Matthew Gribble, Dammy Shittu, Scott P. Collins, Chase L. Beisel, Roberto Galizi, Andrea Crisanti
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-24214-5
Popis: Technologies that can halt the spread of gene drives would be highly useful in controlling or reverting their effect. Here the authors use the anti-CRISPR protein AcrIIA4 to inactivate drives in A. gambiae.
Databáze: Directory of Open Access Journals