Wait and watch: A trachoma surveillance strategy from Amhara region, Ethiopia.

Autor: Eshetu Sata, Fikre Seife, Zebene Ayele, Sarah A Murray, Karana Wickens, Phong Le, Mulat Zerihun, Berhanu Melak, Ambahun Chernet, Kimberly A Jensen, Demelash Gessese, Taye Zeru, Adisu Abebe Dawed, Hiwot Debebe, Zerihun Tadesse, E Kelly Callahan, Diana L Martin, Scott D Nash
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: PLoS Neglected Tropical Diseases, Vol 18, Iss 2, p e0011986 (2024)
Druh dokumentu: article
ISSN: 1935-2727
1935-2735
DOI: 10.1371/journal.pntd.0011986&type=printable
Popis: BackgroundTrachoma recrudescence after elimination as a public health problem has been reached is a concern for control programs globally. Programs typically conduct district-level trachoma surveillance surveys (TSS) ≥ 2 years after the elimination threshold is achieved to determine whether the prevalence of trachomatous inflammation-follicular (TF) among children ages 1 to 9 years remains Methods/principal findingsThese post-surveillance surveys, conducted in 2021, were multi-stage cluster surveys whereby certified graders assessed trachoma signs. Children ages 1 to 9 years provided a dried blood spot and children ages 1 to 5 years provided a conjunctival swab. TF prevalence in Metema and Woreta Town were 3.6% (95% Confidence Interval [CI]:1.4-6.4) and 2.5% (95% CI:0.8-4.5) respectively. Infection prevalence was 1.2% in Woreta Town and 0% in Metema. Seroconversion rates to Pgp3 in Metema and Woreta Town were 0.4 (95% CI:0.2-0.7) seroconversions per 100 child-years and 0.9 (95% CI:0.6-1.5) respectively.Conclusions/significanceBoth study districts had a TF prevalence
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