Autor: |
Endrya do Socorro Fôro Ramos, Ulisses Alves Rosa, Geovani de Oliveira Ribeiro, Fabiola Villanova, Flávio Augusto de Pádua Milagres, Rafael Brustulin, Vanessa dos Santos Morais, Mayara Bertanhe, Roberta Marcatti, Emerson Luiz Lima Araújo, Steven S. Witkin, Eric Delwart, Adriana Luchs, Antonio Charlys da Costa, Élcio Leal |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Viruses, Vol 13, Iss 4, p 595 (2021) |
Druh dokumentu: |
article |
ISSN: |
1999-4915 |
DOI: |
10.3390/v13040595 |
Popis: |
Echoviruses (E) are a diverse group of viruses responsible for various pathological conditions in humans including aseptic meningitis, myocarditis, and acute flaccid paralysis. The detection and identification of echovirus genotypes in clinical samples is challenging due to its high genetic diversity. Here, we report the complete genome sequences of nine echoviruses, obtained by next-generation sequencing of 238 fecal samples from individuals with gastroenteritis in regions of Brazil. Detected viruses were classified into six genotypes: Three E1 sequences (BRA/TO-028, BRA/TO-069 and BRA/TO-236), one E3 (BRA/TO-018), one E11 (BRA/TO-086), one E20 (BRA/TO-016), two E29 (BRA/TO-030 and BRA/TO-193), and one E30 sequence (BRA/TO-032). Phylogenetic analysis indicated that the echoviruses E1 and E29 circulating in Brazil are divergent from strains circulating worldwide. The genotype diversity identified in our study may under-represent the total echovirus diversity in Brazil because of the small sample size and the restricted geographical distribution covered by the survey. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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