Salivary immunoglobulin levels and periodontal indices in Brazilian children with and without type 1 diabetes

Autor: Thyciana Rodrigues RIBEIRO, Sara Maria SILVA, Renata Asfor Rocha Carvalho MARTINS, Cláudia Ferreira SANTOS, Paulo Goberlânio de Barros SILVA, Adriana Costa e FORTI, Fábio Wildson Gurgel COSTA, Manassés Claudino FONTELES, Cristiane Sá Roriz FONTELES
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Brazilian Oral Research, Vol 38 (2024)
Druh dokumentu: article
ISSN: 1807-3107
DOI: 10.1590/1807-3107bor-2024.vol38.0043
Popis: Abstract This cross-sectional study evaluated the association between salivary immunoglobulins, plaque index, and gingival index in Brazilian children with and without type 1 diabetes mellitus (DM1). The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for the reporting of observational studies was followed. The DM1 group had 38 children, and an equal number of volunteers matched by sex and age were recruited as controls. Clinical examination was performed for plaque index and gingival index determination. Non-stimulated whole saliva was collected. Concentrations of IgA, IgG, and IgM were determined by ELISA test. Data were tested by the Kolmogorov-Smirnov, Mann-Whitney, and Spearman tests and a multiple linear regression model (p
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