Cardiovascular and metabolic determinants of quality of life in patients with cancer

Autor: Ruben Evertz, Katharina Gödde, Christine Diehl, Miroslava Valentova, Tania Garfias‐Veitl, Friederike Braulke, Gerald G. Wulf, Tobias R. Overbeck, Annalen Bleckmann, Alexander O. König, Pia Weinländer, Sophia Potthoff, Sara Hadzibegovic, Alessia Lena, Ulrich Keller, Ulf Landmesser, Andreas Schuster, Markus S. Anker, Gerd Hasenfuß, Stephan vonHaehling
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: ESC Heart Failure, Vol 10, Iss 1, Pp 167-176 (2023)
Druh dokumentu: article
ISSN: 2055-5822
DOI: 10.1002/ehf2.14175
Popis: Abstract Aims Maintaining quality of life (QoL) in patients with cancer has gathered significant interest, but little is known about its major determinants. We sought to identify determinants of QoL in patients undergoing cancer treatment as well as in treatment‐naïve patients about to commence such therapy. Methods and results QoL was assessed in 283 patients with cancer using the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 questionnaire. All patients underwent a battery of tests including physical examination, resting electrocardiogram, hand grip strength, and biochemistry assessment. Using multivariable logistic regression, we found that age [odds ratio (OR) 0.954, 95% confidence interval (CI) 0.916–0.994], resting heart rate (OR 1.036, 95% CI 1.004–1.068), hand grip strength (OR 0.932, 95% CI 0.878–0.990), and the presence of cachexia (OR 4.334, 95% CI 1.767–10.631) and dyspnoea (OR 3.725, 95% CI 1.540–9.010; all P
Databáze: Directory of Open Access Journals