Tirofiban-Induced Thrombocytopenia Occurring with Crohn’s Disease

Autor: Toni Ibrahim, Fady El Karak, Assem Araji, Elie El Rassy
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Case Reports in Cardiology, Vol 2016 (2016)
Druh dokumentu: article
ISSN: 2090-6404
2090-6412
DOI: 10.1155/2016/4605139
Popis: A 69-year-old man, with severe refractory Crohn’s disease, presented with acute coronary syndrome that required angioplasty. He developed severe tirofiban-induced thrombocytopenia (TIT) heralded by type I allergic reaction that required steroids and a combination of antihistamine H1 and antihistamine H2 for symptomatic management. The thrombocytopenia spontaneously resolved uneventfully in 48 hours thereafter. This case report suggests a possible association between TIT and inflammatory bowel disease. Therefore, strict monitoring of the platelet count is required in patients who develop allergic reactions to tirofiban.
Databáze: Directory of Open Access Journals