ALTERNATIVE APPROACHES TO MEDICAL ABORTION

Autor: K. Telbiyska, M. Angelova
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Trakia Journal of Sciences, Vol 22, Iss 1, Pp 74-79 (2024)
Druh dokumentu: article
ISSN: 1313-3551
DOI: 10.15547/tjs.2024.01.011
Popis: Medical abortion involving various pharmacological agents has demonstrated high levels of complete uterine evacuation. Alternative approaches involving letrozole, mifepristone, methotrexate used synergically with misoprostol are non-invasive elective methods of achieving complete abortion. Abortion induced by mifepristone, letrozole and misoprostol results in complete evacuation in 98% of the cases.The synergic effect of mifepristone and misoprostol achieves 98.2% effectiveness. Medical management of abortion with letrozole and misoprostol has 97.8% complete expulsion. Current reports of surgical termination of pregnancy reveal 97% effectiveness. Letrozole destabilizes the dominant position of mifepristone but the reports of its non-significant prevalence regarding complete abortion should be verified by a larger number of studies. Medical abortion is non-inferior in its effectiveness to surgical abortion and is unambiguously likely to become in the future the principal recommendation for termination of early pregnancy.
Databáze: Directory of Open Access Journals