Extremity risk factors of sepsis for gastrointestinal endoscopy in patients with liver cirrhosis

Autor: Yi-Chia Chan, Chao-Long Chen, Chih-Chi Wang, Chih-Che Lin, Chee-Chien Yong, King-Wah Chiu, Keng-Liang Wu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMC Gastroenterology, Vol 22, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 1471-230X
DOI: 10.1186/s12876-022-02124-0
Popis: Abstract Background Liver cirrhosis is a well-known risk factor of sepsis after emergent gastrointestinal (GI) endoscopy. Elective GI endoscopy before living donor liver transplantation (LDLT), however, may also carry the septic risk among these patients. Methods This retrospective study reviewed the medical records of 642 cirrhotic recipients who underwent GI endoscopy from 2008 to 2016. We analyzed the incidence and risk factors of post-endoscopy sepsis during 2008–2012 (experience cohort). Our protocol changed after 2013 (validation cohort) to include antibiotic prophylaxis. Results In experience cohort, 36 cases (10.5%) of the 342 LDLT candidates experienced sepsis within 48 h after endoscopy. The sepsis rate was significantly higher in patients with hepatic decompensation than patients without (22.2% vs. 9.6% vs. 2.6% in Child C/B/A groups respectively; ×2 = 20.97, P
Databáze: Directory of Open Access Journals
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