Autor: |
Yi-Chia Chan, Chao-Long Chen, Chih-Chi Wang, Chih-Che Lin, Chee-Chien Yong, King-Wah Chiu, Keng-Liang Wu |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-11 (2022) |
Druh dokumentu: |
article |
ISSN: |
1471-230X |
DOI: |
10.1186/s12876-022-02124-0 |
Popis: |
Abstract Background Liver cirrhosis is a well-known risk factor of sepsis after emergent gastrointestinal (GI) endoscopy. Elective GI endoscopy before living donor liver transplantation (LDLT), however, may also carry the septic risk among these patients. Methods This retrospective study reviewed the medical records of 642 cirrhotic recipients who underwent GI endoscopy from 2008 to 2016. We analyzed the incidence and risk factors of post-endoscopy sepsis during 2008–2012 (experience cohort). Our protocol changed after 2013 (validation cohort) to include antibiotic prophylaxis. Results In experience cohort, 36 cases (10.5%) of the 342 LDLT candidates experienced sepsis within 48 h after endoscopy. The sepsis rate was significantly higher in patients with hepatic decompensation than patients without (22.2% vs. 9.6% vs. 2.6% in Child C/B/A groups respectively; ×2 = 20.97, P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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