Chordoid Meningioma: Literature Review

Autor: Carlos Roberto Massella Junior, Marcus Vinicius de Morais, Rafael Pontes Figueiredo, Andrezza Garcia Morales, Paulo Mácio Porto de Melo
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Brazilian Neurosurgery, Vol 39, Iss 01, Pp 012-015 (2020)
Druh dokumentu: article
ISSN: 0103-5355
2359-5922
DOI: 10.1055/s-0039-3402490
Popis: Chordoid meningiomas (CMs) are a rare subgroup of tumors, accounting for ∼ 0.5% of all meningiomas. Chordoid meningioma tumors correspond to World Health Organization (WHO) Grade II lesions and behave aggressively, with an increased likelihood of recurrence. There are few genetic studies about CMs, but we understand that there is deletion at many chromosomal loci. Histologically, CMs are characterized by strands and cords of meningothelial cells arranged in a mucinous stroma. Morphologically, it can mimic other chondroid and myxoid tumors within the brain and its vicinity, thus posing a diagnostic challenge. Chordoid meningiomas have an aggressive clinical course and a propensity to recur compared with classical meningiomas. The goal of the treatment is surgery, with total resection of the tumor; however, due to its high degree of recurrence, radiotherapy is often necessary as an adjuvant treatment.
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