| Autor: |
Takehito Ehara, Masato Kitazawa, Nao Hondo, Shugo Takahata, Yuta Yamamoto, Makoto Koyama, Motohiro Okumura, Satoshi Nakamura, Shigeo Tokumaru, Futoshi Muranaka, Yusuke Miyagawa, Yuji Soejima |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Case Reports in Oncology, Vol 13, Iss 1, Pp 145-152 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1662-6575 |
| DOI: |
10.1159/000505323 |
| Popis: |
Disseminated carcinomatosis of the bone marrow (DCBM) in colorectal cancer is an extremely rare complication with a poor prognosis. Here, we report a case of DCBM due to rectal cancer successfully treated with a combination of FOLFOX and an anti-epidermal growth factor receptor (EGFR) agent. The patient was a 38-year-old man diagnosed with rectal cancer with multiple bone and para-aortic lymph node metastases complicated by disseminated intravascular coagulation (DIC). He first recovered from DIC following cotreatment with FOLOX plus cetuximab; subsequently, the second attack was successfully treated with FOLFOX plus panitumumab. His initial condition was extremely poor, but he survived with two FOLFOX plus anti-EGFR regimens and died 333 days after introduction of chemotherapy. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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