Optimal combinations of systolic and diastolic blood pressure in Korea: A nationwide population‐based cohort study

Autor: Won‐Jun Choi, Hye‐Sun Lee, Jung Hwa Hong, Hyuk‐Jae Chang, Ji‐Won Lee
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: The Journal of Clinical Hypertension, Vol 23, Iss 1, Pp 85-95 (2021)
Druh dokumentu: article
ISSN: 1751-7176
1524-6175
DOI: 10.1111/jch.14125
Popis: Abstract We investigated the optimal combinations of systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels for lowest mortality in participants not taking hypertensive medication at the study baseline using nationwide representative databases. Survival rates and hazard ratios (HRs) were calculated using Kaplan‐Meier curves and multivariable Cox regression analyses. The discriminatory ability for clinical outcomes was assessed by Harrell's C‐index analysis. A survival spline curve was presented, and Classification and Regression Tree (CART) analysis was performed. SBP ≥ 140 group and DBP ≥ 90 group had the highest risk of mortality. Within SBP
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