Prophylactic anticoagulation in nephrotic syndrome prevents thromboembolic complications

Autor: Sarah Kelddal, Karen Marie Nykjær, Jon Waarst Gregersen, Henrik Birn
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Nephrology, Vol 20, Iss 1, Pp 1-6 (2019)
Druh dokumentu: article
ISSN: 1471-2369
DOI: 10.1186/s12882-019-1336-8
Popis: Abstract Background An increased incidence of thromboembolic events (TE) are reported in nephrotic syndrome (NS) leading to recommendations for prophylactic anticoagulation (PAC). However, as no randomized clinical trial has established the efficacy or risks associated with PAC, guidelines are empiric or substantiated only by estimates of risks and benefits. This study evaluates the risk of TE and hemorrhagic complications in patients with NS treated with PAC and compares to patients not receiving PAC. Methods We included patients diagnosed with NS from two Danish nephrology departments with different practices for the use of PAC. Patients were included if presenting with NS from September 2006 to January 2012, a P-albumin
Databáze: Directory of Open Access Journals