The role of nitric oxide and lipid peroxidation in patients with Plasmodium vivax malaria

Autor: Polat G., Aslan G., Eskandari G.H., Delialioğlu N., Bağdatoğlu Ö., Atik U.
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Zdroj: Parasite, Vol 9, Iss 4, Pp 371-374 (2002)
Druh dokumentu: article
ISSN: 1252-607X
1776-1042
DOI: 10.1051/parasite/2002094371
Popis: In this study, we investigated the role of nitric oxide metabolism and lipid peroxidation in patients with P. vivax malaria. The levels of nitrite and nitrate were analyzed using a procedure based on the Griess reaction and malondialdehyde levels which index of lipid peroxidation was determined by thiobarbituric acid reaction. The levels of nitrite/nitrate and malondialdehyde in patients were higher than controls and found to be statistically significant (p < 0.001). We performed this study to determine whether nitric oxide and lipid peroxidation is produced during blood-stage P. vivax malaria. This present study shows that lipid peroxidation occurs in P. vivax malaria. The levels of nitric oxide are associated with lipid peroxidation in this disease.
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