| Autor: |
Renuka Mahajan, Prakash Itankar |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Digital Chinese Medicine, Vol 3, Iss 3, Pp 188-198 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2589-3777 |
| DOI: |
10.1016/j.dcmed.2020.09.005 |
| Popis: |
Objective: To investigate the antioxidant, antimicrobial and wound healing potential of Helicteres isora Linn. leaf extracts. Methods: The petroleum ether, chloroform, acetone, ethanol and hydroalcoholic extracts of leaves were screened for phytochemicals. The 1,1-diphenyl-2-picrylhydrazyl (DPPH), nitric oxide (NO) radical scavenging tests and reducing power assays were performed to measure antioxidant activity; disc diffusion methods were used to evaluate antimicrobial potential. Wound healing activity was evaluated by incision and excision wound rat models. Results: The extracts contained mainly sterols and flavonoids. The hydroalcoholic extract showed remarkable antioxidant and antimicrobial potential and significant (P < 0.05) wound healing activity. Conclusions: The identified activities of the hydroalcoholic extract may be attributable to its constituent phytochemicals. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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