Non-Invasive Extraction of Mechanical Skin Parameters by Ultrasonic Image Processing: Validation by Invasive Tensiometric Method
| Autor: | Mohadese Estaji Mohadese Estaji, Manijhe Mokhtari Dizaji, Mansoureh Movahedin |
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| Jazyk: | perština |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | مجله علمی دانشگاه علوم پزشکی کردستان, Vol 27, Iss 1, Pp 126-136 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1560-652X 2345-4040 |
| Popis: | Background and aim: Conventional methods for the skin aging are based mainly on physiological or biochemical observations. The aim of this study is to provide a non-invasive method based on the extraction of biomechanical parameters of the skin resulting from the processing of sequential high-frequency ultrasound images in order to investigate the process of skin lesions. Material and Methods: Consecutive ultrasound images of the epidermal and dermal layers were recorded and saved with a 40 MHz imaging system. In order to evaluate the process of skin damage, 25 C57BL6 mice were exposed to UVB radiation. The mechanical parameters of the skin derived from the processing of sequential ultrasound images were also estimated weekly with the motion estimation algorithm (gradient and block matching) during the injury generation process and results were reported as a mean and standard deviation. Validation of the method was performed by invasive tensiometric test. Correlation between the two methods was performed by Pearson correlation analysis. Statistical repeated measures analysis of variance was used to compare the statistical trend of changes over 5 weeks. Results: Significant correlation was obtained between elasticity extracted from non-invasive ultrasonic image processing method and invasive tensiometric method with a correlation coefficient of more than 0.79. By processing the sequential ultrasound images, the axial elastic and the shear modulus of the skin layers were significantly increased, which indicate the increased skin firmness during the ultraviolet radiation (p |
| Databáze: | Directory of Open Access Journals |
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