| Autor: |
Morrison A.V., Popovich V.I., Morrison V.V. |
| Jazyk: |
ruština |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Саратовский научно-медицинский журнал, Vol 11, Iss 4, Pp 526-529 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
2076-2518 |
| Popis: |
Purpose: to study biochemical indices of peripheral blood which show organs functional changes. Material and Methods. The experiments were carried out on white mice in dynamics development of pseudomonas aeruginosa caused by intraperitoneal injection of various dosage of exotoxin A. Results. The dosage-dependent disturbances in activity of transaminases, a-HBDH, in content of proteins, lipids and cholesterol were revealed. The received data have determined the hepatotoxic effect of pseudomonas aeruginosa exotoxin A on changes of biochemical blood markers of liver function. Conclusion. The expressed hepatotoxic effect of Pseudomonas aeruginosa exotoxin A has been determined during all the phases of experiment even at sublethal toxin dose. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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