Comparison of pharmacological activity of hawthorn fruits preparations
| Autor: | Vladimir A. Kurkin, Elena N. Zaitceva, Elena V. Avdeeva, Viktoriya V. Stenyaeva, Ilnur Kh. Shaikhutdinov, Alina V. Zhdanova |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Наука и инновации в медицине, Vol 5, Iss 2, Pp 136-139 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2500-1388 2618-754X |
| DOI: | 10.35693/2500-1388-2020-5-2-136-139 |
| Popis: | Objectives a comparative study of antidepressant activity and diuretic action of water and water-alcohol preparations of the fruits ofCrataegus sanguinea Pall.andCrataegus submollis Sarg. Materials and methods.The study covers the water and alcohol-water extracts from the fruits of hawthorn blood-red (Crataegus sanguinea Pall.) and Quebec hawthorn (Crataegus submollis Sarg.). The comparative study of the antidepressant activity and the diuretic action of the preparations was carried out on white mongrel rats of both sexes. Results.The liquid extracts of fruitsCrataegus sanguinea Pall.andCrataegus submollis Sarg. at a dose of 100 l/kg revealed an antidepressant activity. Decoctions ofCrataegus sanguinea Pall.andCrataegus submollis Sarg. at a dose of 100 l/kg had a pronounced diuretic and saluretic activity. Pharmacotherapeutic effects of the studied preparations can be explained by the presence of flavonoids in them. Conclusion.The preparations of the fruits ofCrataegus sanguinea Pall.andCrataegus submollis Sarg.can be recommended as antidepressant and diuretic agents. The fruits ofCrataegus submollis Sarg. are the promising medicinal plant raw materials. |
| Databáze: | Directory of Open Access Journals |
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