Parathyroid carcinoma: case report
| Autor: | Matheus Henrique de Freitas Silva, Pedro Otávio de Resende Morais, Thaís Andrade de Souza, André Luis Ribeiro Muniz, Bárbara C Silva, Thiago Bechara Noviello, Marcella Menezes Andrade |
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| Jazyk: | portugalština |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Medicina, Vol 50, Iss 6 (2018) |
| Druh dokumentu: | article |
| ISSN: | 2176-7262 0076-6046 |
| DOI: | 10.11606/issn.2176-7262.v50i6p390-397 |
| Popis: | Parathyroid carcinoma (PC) is an uncommon pathology which has propaedeutic and therapeutic peculiarities. In general, it presents as symptomatic primary hyperparathyroidism, that corresponds to only 1% in this subgroup. Both the clinical and histological diagnosis of PC are difficult due to inconsistent criteria. Laboratorial exams commonly present hypercalcemia and PTH well-above the reference value. Surgery is the only curative and effective treatment for parathyroid carcinoma. Case report: Patient M.P.R.L., 48 years old, female, melanodermic, native and from Felisburgo - MG. The disease had been progressing for 2 years with progressive weakness, anemia, renal dysfunction, chronic pain and weight loss (about 15 kg in last five months), associated with PTH-dependent hypercalcemia and renal function decline. A cervical study showed the presence of two thyroid nodules whereas a parathyroid scintigraphy showed no evidence of glands hyperplasia or adenoma. She was admitted to the Santa Casa Hospital of Belo Horizonte for a propaedeutic and therapeutic management of the presented profile. |
| Databáze: | Directory of Open Access Journals |
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