Evaluation Value of Serum Markers Combined with miRNA-let-7 in Chemotherapy Effect and Prognosis of Glioblastoma Multiforme

Autor: Jie ZHAO, Qiuxia SHI, Qiang FU
Jazyk: čínština
Rok vydání: 2024
Předmět:
Zdroj: Zhongliu Fangzhi Yanjiu, Vol 51, Iss 8, Pp 684-689 (2024)
Druh dokumentu: article
ISSN: 1000-8578
DOI: 10.3971/j.issn.1000-8578.2024.23.1101
Popis: ObjectiveTo analyze the predictive effect of miRNA-let-7 combined with serum markers on the chemotherapy effect and prognosis of glioma (GBM) patients. MethodsWe collected the data of 25 patients with GBM. Twenty healthy volunteers were included as the control group. Fasting serum samples were collected. The levels of let-7b, let-7d, and let-7e in serum samples were analyzed by quantitative real-time PCR. ResultsCompared with the control group, the levels of let-7b (192.5±18.71 vs. 98.13±11.68, t=6.42, P
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