| Autor: |
Gregory Vlacich, Andrew Ballard, Shahed N. Badiyan, Matthew Spraker, Lauren Henke, Hyun Kim, A. Craig Lockhart, Haeseong Park, Rama Suresh, Yi Huang, Cliff G. Robinson, Jeffrey D. Bradley, Pamela P. Samson |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Clinical and Translational Radiation Oncology, Vol 30, Iss , Pp 19-25 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6308 |
| DOI: |
10.1016/j.ctro.2021.06.007 |
| Popis: |
Background and purpose: Radiation dose escalation to improve poor outcomes with chemoradiation in locally advanced esophageal carcinoma is limited in part by increased toxicity. This Phase I study investigates the use of IMRT to improve tolerability of dose escalation. Materials and methods: A single-institution, prospective study was conducted between 2007 and 2013 for individuals with inoperable esophageal carcinoma. Gross disease received 60 Gy in 30 fractions and at-risk sites received 54 Gy with simultaneous integrated boost. Concurrent chemotherapy primarily consisted of cisplatin/5-FU. The primary objective was to assess feasibility ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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