| Autor: |
Júlia Mestres, Francesca Leonardi, Klaus Mathwig |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Micromachines, Vol 13, Iss 3, p 362 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2072-666X |
| DOI: |
10.3390/mi13030362 |
| Popis: |
Electrochemical sensors are powerful tools for the detection and real-time monitoring of a wide variety of analytes. However, the long-term operation of Faradaic sensors in complex media is challenging due to fouling. The protection of the electrode surface during in vivo operation is a key element for improving the monitoring of analytes. Here, we study different EUDRAGIT® controlled release acrylate copolymers for protecting electrode surfaces. The dissolution of these polymers—namely EUDRAGIT® L 30 D-55 and EUDRAGIT® FS 30 D—is triggered by a change in pH of the environment, and it is electrochemically monitored by detecting electrode access by means of a redox probe. The full dissolution of the polymer is achieved within 30 min and the electrode response indicates a complete recovery of the original electrochemical performance. We demonstrate that amperometric sensing is a practical and straightforward technique for real-time and in situ sensing of EUDRAGIT® dissolution profiles. It will find future applications in determining the protection of polymer electrode coating in real matrices and in vivo applications. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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